The NormandyFlowChem platform has a large range of modular, versatile and state-of-the-art equipment including "all-in-one" flow chemistry systems, in-line/on-line analysis devices and a wide range of pumps and accessories. Thereby, each reaction is conducted with the appropriate combination of equipment.

« All-in-one » flow chemistry systems

These systems include reagent distribution (pumps) and reaction conditions controle (temperature, activation method...)

CORNING AFR G1 SiC

  • Three liquid dosing lines, including one PTFE (max 100 mL/min each)
  • One gas dosing line
  • 10 silicon carbide plate reactors of 9 mL with patented design allowing very efficient mixing and heat transfer
  • Reaction temperature from - 40 to 200 °C
  • Kilolab/pilot scale transposition
  • FDA and cGMP compliant

Corning AFR LabPhotoReactor

  • Two HPLC pumps (max 10 mL/min each)
  • One gas dosing line
  • 2.7 mL glass plate reactor with patented design for very efficient mixing and heat transfer
  • Reaction temperature from -40 °C to 200 °C
  • Irradiation to 365, 385, 405, 475 and 610 nm

VAPOURTEC R-SERIES R2S

  • Two peristaltic pumps with high chemical compatibility (max 10 mL/min each)
  • 4 spots for temperature regulated reactors (from -20 to 250 °C)
  • Compatible with Vapourtec photochemistry and electrochemistry modules
  • Automation possible

VAPOURTEC RS-300 R2C/R2S

  • Two HPLC pumps (max 10 mL/min each)
  • Two peristaltic pumps with high chemical compatibility (max 10 mL/min each)
  • 4 spots for temperature regulated reactors (from -20 to 250 °C)
  • Compatible with Vapourtec photochemistry and electrochemistry modules
  • Automation possible

VAPOURTEC E-SERIES

  • Three peristaltic pumps with very good chemical compatibility (max 10 mL/min each)
  • 3 spots for temperature regulated reactors (from -20 to 150 °C)
  • Compatible with Vapourtec photochemistry and electrochemistry modules

In-line/On-line analysis

These devices enable real-time monitoring and analysis of flow processes (conditions stability over time, reaction monitoring, short lifetime reaction intermediates observation...) but also potential auto-optimisation of reaction conditions.

MAGRITEK SPINSOLVE ULTRA X 80

  • NMR analysis for 5 nuclei: 1H, 13C, 19F, 31P, 7Li
  • 1D and 2D experiments (H-H, H-C, H-F, C-P)
  • Solvent signals suppression
  • In-line/On-line monitoring
  • Automation possible

METTLER TOLEDO REACTIR 15

  • Compatible with low temperatures and corrosives conditions
  • Good temporal resolution
  • In-line/On-line monitoring
  • Automation possible

Additionnal equipment

Flow chemistry processes can be achieved with all-in-one systems, assembly of stand-alone modules, or combination of all these elements.

Pumps
- 4 Syrris Asia continuous syringes pumps
- 3 Flom UI HPLC pumps including one with max 100 mL:min flowrate
- 1 Vapourtec SF-10 peristaltic pump
- 17 Harvard Apparatus PhD Ultra syringes pumps
- 3 Harvard Apparatus Elite 11 syringes pumps
- 3 Chemyx F6000X syringes pumps
- Several Bronkhorst gas mass-flow controller (MFC)

Corning Low-Flow skid with 4 glass plates reactors and two temperature zones

Vapourtec UV-150 photoreactors with appropriate lamps:
- Low Pressure Hg UVC 254 nm
- Low Pressure Hg UVB 310 nm
- Low Pressure Hg UVA 370 nm
– LED 365 nm
– LED 405 nm
– LED 430 nm
– LED 450 nm
– LED 470 nm
– LED 525 nm
– LED CW

Vapourtec Ion electrochemistry module
IKA Electrochemical reactor